bacteria

Convergent amino acid signatures in polyphyletic Campylobacter jejuni sub-populations suggest human niche tropism

Human infection with the gastrointestinal pathogen C. jejuni is dependent upon the opportunity for zoonotic transmission and the ability of strains to colonize the human host. Certain lineages of this diverse organism are more common in human …

Bayesian cluster analysis with applications to pathogen population genomics

Identifying similarity patterns in heterogeneous observations is a very common problem in many branches of science. When the similarities and dissimilarities are encoded by a group structure, the task of dividing the observed sample into an unknown …

Dense genomic sampling identifies highways of pneumococcal recombination

Evasion of clinical interventions by Streptococcus pneumoniae occurs through selection of non-susceptible genomic variants. We report whole-genome sequencing of 3,085 pneumococcal carriage isolates from a 2.4 km2 refugee camp. This sequencing …