synergy-score

Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer

High-throughput drug sensitivity screening has been utilized for facilitating the discovery of drug combinations in cancer. Many existing studies adopted a dose-response matrix design, aiming for the characterization of drug combination sensitivity …

DrugComb - an integrative cancer drug combination data portal

Drug combination therapy has the potential to enhance efficacy, reduce dose-dependent toxicity and prevent the emergence of drug resistance. However, discovery of synergistic and effective drug combinations has been a laborious and often …